Archive for May, 2011


There are numerous medications available for acid reflux but which medication really works? Acid reflux medicines are usually combined with GERD diet to complete the treatment. Antacids remain the medicine of choice even if potent medications are developed for the treatment of acid reflux. Based on medical studies, this medicine neutralizes the acid in the stomach to stop reflux of acid. Although this is the popular choice, the action of antacid is brief and thus requires another medication to help prolong the action. Antacids are removed from the empty stomach much faster, usually in less than one hour and the acid then form again. In order to have a better effect take the medicine an hour after meals or before acid reflux begins after a meal. To make the antacid stay longer inside the stomach and become effective longer, it is best to take the medicine after meal.

Antacids as acid reflux medicines can be an aluminium-, magnesium- or calcium-based. The calcium based antacid stimulates the release of gastrin from the stomach and duodenum. The hormone that is responsible for the stimulation of acid secretion in the stomach is gastrin. After the direct acid-neutralizing effect of calcium carbonate, the secretion of acid rebounds. Overproduction of acid is the result of the release of gastrin.

Another medication used in the treatment of GERD is the histamine antagonists. Histamine stimulates acid production by the stomach. Once released in the stomach, the medicine attaches to receptors on the stomach’s cells and stimulates the cells to create acid. Histamine antagonist blocks the histamine receptor and prevents it from stimulating the acid-producing cells. Since it is particularly essential for the stimulation of acid after meals, histamine is best if taken thirty minutes before meals. This is because the H2 antagonists will be at peak level in the body after the meal when acid is producing in the stomach. It can also be taken before bedtime to stop the production of acid during nighttime.

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